RICERCA ITALIANA     

Programmi di ricerca simili:

• 1 - Ruolo della proteolisi intracellulare nella regolazione della risposta immunitaria innata ed acquisita.
• 2 - Interazioni tra immunità innata ed immunità adattativa: dalla biologia alla clinica
• 3 - cellule staminali: programmi genetici e proprietà biologiche, prospettive di applicazioni cliniche
• 4 - I membri della famiglia del TNF nella modulazione del differenziamento cellulare e dell'attività antitumorale
• 5 - Il differente potenziale rigenerativo tra progenitori miocardici residenti e cellule staminali extracardiache nella ricostituzione del cuore
• 6 - Endometriosi: fattori biomolecolari di evoluzione
• 7 - I linfociti T gamma/delta come effettori della risposta immune nelle malattie tumorali: meccanismi di attivazione ed applicazioni cliniche
• 8 - Regolazioni epigenetiche tra cellule mesenchimali e cellule di carcinoma mammario.
• 9 - CELLULE EMOPOIETICHE GENETICAMENTE MODIFICATE PER LA TERAPIA DEI TUMORI
• 10 - Meccanismi di danno della beta cellula e strategie di prevenzione della funzione beta cellulare nel diabete di tipo 1

Classificazione scientifico-disciplinare

• Area scientifico disciplinare: Scienze mediche
  • PATOLOGIA GENERALE
  • MEDICINA INTERNA
  • MALATTIE DEL SANGUE
  • REUMATOLOGIA

Classificazione brevettuale

• CHEMISTRY; METALLURGY
  • BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF (biocides, pest repellants or attractants, or plant growth regulators, containing micro-organisms, viruses, microbial fungi, enzymes, fermentates or substances produced by or extracted from micro-organisms or animal material A01N63/00; food compositions A21, A23; medicinal preparations A61K; chemical aspects of, or use of materials for, bandages, dressings, absorbent pads or surgical articles A61L; fertilisers C05); PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS (preservation of living parts of humans or animals A01N1/02); MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA (micro-biological testing media C12Q)

Classificazione geografica

• Regione: Toscana

Bibliografia

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31. Romagnani C, et al. Identification of HLA-E-specific alloreactive T lymphocytes: a cell subset that undergoes preferential expansion in mixed lymphocyte culture and displays a broad cytolytic activity against allogeneic cells. Proc Natl Acad Sci USA 99:11328, 2002.
32. Pietra G, et al. The analysis of the natural killer-like activity of human cytolytic T lymphocytes revealed HLA-E as a novel target for TCR alpha/beta-mediated recognition. Eur J Immunol 31:3687, 2001.
33. Tomasec P, et al. Surface expression of HLA-E, an inhibitor of natural killer cells, enhanced by human cytomegalovirus gpUL40. Science 287:1031, 2000.
34. Pietra G., et al. Recognition of Cytomegalovirus-derived peptides by human CD8+ cytolytic T lymphocytes. PNAS, 100, 10896-10901, 2003.
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39. Krampera M, et al. Bone marrow mesenchymal stem cells inhibit the response of naïve and memory antigen-specific T cells to their cognate peptide. Transplantation 101: 3722-29, 2003
40. Aggarwal, S., Pittenger, M.F. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood. 105:1815-1822, 2005.
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Parole Chiave

CELLULE DENDRITICHE; CELLULE REGOLATORIE; CELLULE T REGOLATORIE; CELLULE STAMINALI MESENCHIMALI; METABOLISMO DEL TRIPTOFANO; PROFILI TRASCRIZIONALI; POLARIZZAZIONE TH1/TH2